CAS:862507-23-1
862507-23-1
CAS号：862507-23-1
品名：5-[2-(叔丁基)-4-(4-氟苯基)-1H-咪唑-5-基]-3-(2,2-二甲基丙基)-3H-咪唑并[4,5-b]吡啶-2-胺甲磺酸盐5-[2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)imidazo[4,5-b]pyridin-2-amine,methanesulfonicacid
中文别名：5-[2-(叔丁基)-4-(4-氟苯基)-1H-咪唑-5-基]-3-(2,2-二甲基丙基)-3H-咪唑并[4,5-b]吡啶-2-胺甲磺酸盐
英文别名：RalimetinibMesylate;UNII-QUW7B71FO9;
分子式：C26H37FN6O6S2
分子量：612.737
精确质量：612.22
Psa：211.64
MDL号：MFCD27918654
密度：
沸点：634.4ºC at 760 mmHg
闪点：337.5ºC
简介：LY2228820isanovelandpotentp38MAPKinhibitorwithpotentantiinflammatoryactivity.LY2228820significantlyinhibitedphosphorylationofMAPKAPK2and/orHSP27,downstreamtargetsofp38MAPK,inbothmultiplemyeloma(MM)celllinesandLT-BMSCs.LY2228820isapotentialcandidatetoimproveMMpatientoutcomebothbyenhancingtheeffectofBortezomibandbyreducingosteoskeletalevents.
MAPK
