CAS:285983-48-4
285983-48-4
CAS号：285983-48-4
品名：1-[2-(4-甲基苯基)-5-叔丁基吡唑-3-基]-3-[4-(2-吗啉-4-基乙氧基)萘-1-基]脲1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea
中文别名：脲,N-[3-(1,1-二甲基乙基)-1-(4-甲基苯基)-1H-吡唑-5-基]-N'-[4-[2-(4-吗啉基)乙氧基]-1-萘基];达马莫德;多马莫德;
英文别名：BIRB796(Doramapimod);Doramapimod;Kinome_2137;1kv2;BIRB796;UNII-HO1A8B3YVV;
分子式：C31H37N5O3
分子量：527.657
精确质量：527.29
Psa：80.65
MDL号：MFCD09752957
密度：1.2g/cm3
沸点：631.6ºC at 760mmHg
闪点：335.8ºC
折射率：1.619
蒸汽压：7.36E-16mmHg at 25°C
简介：Doramapimodisahighlypotentinhibitorofp38mitogen-activatedproteinkinase(MAPK).Doramapimodisapotentialagentforthetreatmentofinflammatorydiseases.Doramapimodblocksbaselineandbortezomib-triggeredupregulationofp38MAPKandHsp27phosphorylationleadingtoenhancedcytotoxicityandcaspaseactivation.
MAPK
