CAS:133865-89-1
133865-89-1
CAS号：133865-89-1
品名：沙芬酰胺(2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide
中文别名：(S)-2-[[4-[(3-氟苯甲基)氧]苯甲基]氨基]丙酰胺;
英文别名：(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propionamide;(S)-(+)-2-[4-(3-fluorobenzyloxy)benzylamino]-propanamide;(2S)-2-[4-(3-fluorobenzyloxy)benzylamino]propionamide;Safinamide;
分子式：C17H19FN2O2
分子量：302.343
精确质量：302.143
Psa：64.35
UNII号：90ENL74SIG
密度：1.189 g/cm3
沸点：476.7ºC at 760 mmHg
折射率：1.569
蒸汽压：2.98E-09mmHg at 25°C
简介：Safinamide(INN;brandnameXadago,formerdevelopmentalcodenameEMD-1195686)isadrugindicatedforthetreatmentofParkinson'sdiseasewithmultiplemethodsofaction.In2007,aPhaseIIIclinicaltrialwasstarted.Itwasscheduledtorununtil2011.ThecompoundwasoriginallydiscoveredatFarmitalia-CarloErba,firstpublishedin1998anddevelopedbyNewronPharmaceuticals,whichsoldtherightstoMerck-Seronoin2006.InOctober2011Merck-SeronoannouncedthattheywouldgiveallrightstodevelopthecompoundbacktoNewron.
膜转运/离子通道
