CAS:934541-31-8
934541-31-8
CAS号：934541-31-8
品名：TAK-901
中文别名：5-[3-(乙基磺酰基)苯基]-3,8-二甲基-N-(1-甲基-4-哌啶基)-9H-吡啶并[2,3-b]吲哚-7-羧酰胺;
英文别名：5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methylpiperidin-4-yl)-9H-pyrido[2,3-b]indole-7-carboxamide;5-[3-(Ethylsulfonyl)phenyl]-3,8-dimethyl-N-(1-methyl-4-piperidinyl)-9H-pyrido[2,3-b]indole-7-carboxamide;5-(3-(ethylsulfonyl)phenyl)-3,8-dimethyl-N-(1-methylpiperidin-4-yl)-9H-pyrido[2,3-b]indole-7-carboxamide;TAK901;
分子式：C28H32N4O3S
分子量：504.644
精确质量：504.22
Psa：103.54
MDL号：MFCD18782651
密度：1.335 g/cm3
沸点：761.708ºC at 760 mmHg
闪点：414.467ºC
简介：AnovelAuroraBkinaseinhibitorwithpotentialantineoplasticactivity.ItbindstoandinhibitstheactivityofAuroraB,whichmayresultinadecreaseintheproliferationoftumorcellsthatoverexpressAuroraB.AuroraBisapositiveregulatorofmitosisthatfunctionsintheattachmentofthemitoticspindletothecentromere;thesegregationofsisterchromatidstoeachdaughtercell;andtheseparationofdaughtercellsduringcytokinesis.
细胞周期
