CAS:1190307-88-0
1190307-88-0
CAS号：1190307-88-0
品名：索非布韦sofosbuvir
中文别名：索非布韦
英文别名：Sofosbuvir;GS-7977;propan-2-yl(2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate;SOFOSBUVIR;(S)-2-{(S)-[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylamino}propionicacidisopropylester;
分子式：C22H29FN3O9P
分子量：529.453
精确质量：529.163
Psa：167.99
UNII号：WJ6CA3ZU8B
密度：1.4±0.1g/cm3
折射率：1.573
储存条件：-20°C
简介：PSI-7977isaprodrugthatismetabolizedtotheactiveantiviralagent2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphateandiscurrentlybeinginvestigatedinphase3clinicaltrialsforthetreatmentofhepatitisC.StudieshaveprofiledPSI-7977asanucleotideinhibitorofhepatitisCvirus,exertingselectiveinhibitoryeffectstowardsHCVNS5Bpolymerase.
用途：用于特定基因型慢性丙型肝炎治疗时，可消除对传统注射药物干扰素（IFN）的需求。
细胞周期
