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CAS:402957-28-2

 402957-28-2

402957-28-2

CAS号:402957-28-2

品名:特拉匹韦telaprevir

中文别名:特拉匹伟;TELAPREVIR;特拉匹伟/VX950;

英文别名:VX-950;Telaprevir;Telaprevir(VX-950);

分子式:C36H53N7O6

分子量:679.849

精确质量:679.406

Psa:179.56

UNII号:655M5O3W0U

密度:1.25 g/cm3

简介:Telaprevir(VX-950),marketedunderthebrandnamesIncivekandIncivo,isapharmaceuticaldrugforthetreatmentofhepatitisCcodevelopedbyVertexPharmaceuticalsandJohnson&Johnson.Itisamemberofaclassofantiviraldrugsknownasproteaseinhibitors.Specifically,telaprevirinhibitsthehepatitisCviralenzymeNS3.4Aserineprotease.TelaprevirisonlyindicatedforuseagainsthepatitisCgenotype1viralinfectionsandhasnotbeenproventohaveaneffectonorbeingsafewhenusedforothergenotypesofthevirus.Thestandardtherapyofpegylatedinterferonandribavirinislesseffectiveongenotype1.

用途:治疗丙肝病毒(HCV)感染

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