CAS号:402957-28-2
品名:特拉匹韦telaprevir
中文别名:特拉匹伟;TELAPREVIR;特拉匹伟/VX950;
英文别名:VX-950;Telaprevir;Telaprevir(VX-950);
分子式:C36H53N7O6
分子量:679.849
精确质量:679.406
Psa:179.56
UNII号:655M5O3W0U
密度:1.25 g/cm3
简介:Telaprevir(VX-950),marketedunderthebrandnamesIncivekandIncivo,isapharmaceuticaldrugforthetreatmentofhepatitisCcodevelopedbyVertexPharmaceuticalsandJohnson&Johnson.Itisamemberofaclassofantiviraldrugsknownasproteaseinhibitors.Specifically,telaprevirinhibitsthehepatitisCviralenzymeNS3.4Aserineprotease.TelaprevirisonlyindicatedforuseagainsthepatitisCgenotype1viralinfectionsandhasnotbeenproventohaveaneffectonorbeingsafewhenusedforothergenotypesofthevirus.Thestandardtherapyofpegylatedinterferonandribavirinislesseffectiveongenotype1.
用途:治疗丙肝病毒(HCV)感染
蛋白酶