CAS:62-50-0
62-50-0
CAS号：62-50-0
品名：甲磺酸乙酯ethylmethanesulfonate
中文别名：甲基磺酸乙酯;甲基磺酸乙酯(EMS);甲烷磺酸乙酯;
英文别名：CB1528;ethylmethanesulfonate;ETHYLMESYLATE;rcrawastenumberu119;EMS;Ethylmesilate;Methanesulfonicacid,ethylester;Ethylmethanesulfonate;methanesulfonicacidethylester;Half-Myleran;
分子式：C3H8O3S
分子量：124.159
精确质量：124.019
Psa：51.75
RTECS号：PB2100000
UNII号：9H154DI0UP
外观与性状：无色液体
密度：1.206g/mLat 20°C
沸点：85-86°C10mm Hg(lit.)
熔点：&< 25ºC
闪点：100 °C
折射率：n20/D 1.418(lit.)
稳定性：Stable. Combustible. Incompatible with water, alkalies, oxidizing agents.
储存条件：Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
安全说明：S53-S23-S36/37/39-S45
危险类别码：R46; R22; R40
WGK Germany：3
危险品运输编码：2810
危险类别：6.1
包装等级：II
危险品标志：T
简介：Ethylmethanesulfonate(EMS)isamutagenic,teratogenic,andpossiblycarcinogenicorganiccompoundwithformulaC3H8SO3.Itproducesrandommutationsingeneticmaterialbynucleotidesubstitution;particularlybyguaninealkylation.Thistypicallyproducesonlypointmutations.Itcaninducemutationsatarateof5x10−4to5x10−2pergenewithoutsubstantialkilling.TheethylgroupofEMSreactswithguanineinDNA,formingtheabnormalbaseO-6-ethylguanine.DuringDNAreplication,DNApolymerasesthatcatalyzetheprocessfrequentlyplacethymine,insteadofcytosine,oppositeO-6-ethylguanine.Followingsubsequentroundsofreplication,theoriginalG:CbasepaircanbecomeanA:Tpair(atransitionmutation).Thischangesthegeneticinformation,isoftenharmfultocells,andcanresultindisease.
用途：用作菌种诱变剂,以及有机合成和癌症的研究。
有机砌块
