CAS:923564-51-6
923564-51-6
CAS号：923564-51-6
品名：ABT-263Navitoclax
中文别名：(R)-4-(4-((4'-氯-4,4-二甲基-3,4,5,6-四氢-[1,1'-联苯]-2-基)甲基)哌嗪-1-基)-N-((4-((4-吗啉-1-(苯硫基)-2-丁基)氨基)-3-((三氟甲基)磺酰基)苯基)磺酰基)苯甲酰胺;
英文别名：ABT263;ABT-263;4-[4-[[2-(4-chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide;(R)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide;
分子式：C47H55ClF3N5O6S3
分子量：974.613
精确质量：973.296
Psa：170.42
UNII号：XKJ5VVK2WD
外观与性状：淡黄色固体
密度：1.41 g/cm3
熔点：114-116ºC
折射率：1.654
简介：Navitoclax(previouslyABT-263)isanexperimentalorallyactiveanti-cancerdrug,whichissimilarinactiontoobatoclax,exceptthatunlikeobatoclax,itdoesnothaveoff-targeteffects.
细胞凋亡
