CAS号:4311-88-0
品名:5-(1H-吲哚-3-基甲基)-3-甲基-2-硫酮-4-咪唑烷酮5-(1H-indol-3-ylmethyl)-3-methyl-2-sulfanylideneimidazolidin-4-one
中文别名:Mth-DL-色氨酸;
英文别名:MTH-DL-Tryptophan;Necrostatin1;Necrostatin-1;methyl-thiohydantoin-tryptophan;Nec-1;MTH-trp;5-indol-3-ylmethyl-3-methyl-2-thioxo-imidazolidin-4-one;NecroptoticInhibitor,Nec-1;
分子式:C13H13N3OS
分子量:259.327
精确质量:259.078
Psa:80.22
MDL号:MFCD00056916
密度:1.4g/cm3
沸点:441.9ºC at 760mmHg
熔点:151ºC
闪点:221.1ºC
折射率:1.737
储存条件:-20ºC
WGK Germany:3
海关编码:2933990090
简介:Necroptosisisaregulatedcaspase-independentcelldeathmechanismthatresultsinmorphologicalfeaturesresemblingnecrosis.Necrostatin-1isaninhibitorofRIP1kinasethatpreventsthedeathofTNF-α-treatedFADD-deficientJurkatcells.Necrostatin-1hasbeenusedtoinvestigatethepathologicalimportanceofnecroptosisinischemicbraininjuryandmyocardialinfarction.
细胞凋亡