CAS:1257044-40-8
1257044-40-8
CAS号：1257044-40-8
品名：维特克拉Venetoclax
中文别名：维奈妥拉;
英文别名：Venclexta(USTradename);Venclyxto(EUTradename);GDC-0199;ABT-199;RG7601;4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide;GDC0199;CS-1155;UNII-N54AIC43PW;
分子式：C45H50ClN7O7S
分子量：868.439
精确质量：867.318
Psa：183.09
UNII号：N54AIC43PW
密度：
简介：Venetoclax(INN,tradenameVenclextaven-KLEKS-tuh,previouslyknownasGDC-0199,ABT-199,andRG7601)isasmallmoleculeoraldrugbeinginvestigatedtotreatchroniclymphocyticleukemia(CLL).In2015,theUnitedStatesFoodandDrugAdministration(FDA)grantedBreakthroughTherapyDesignationtovenetoclaxforpatientswithCLLwhohaverelapsedorhavebeenrefractorytoprevioustreatmentandhavethe17pdeletiongeneticmutation.
细胞凋亡
