CAS:518-28-5
518-28-5
CAS号：518-28-5
品名：鬼臼毒素podophyllotoxin
中文别名：鬼臼脂毒;
英文别名：Furo[3‘,4‘:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-,[5R-(5-,5aα,8a-,9-)]-;Podophyllotoxin;(5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one;
分子式：C22H22O8
分子量：414.405
精确质量：414.131
Psa：92.68
RTECS号：LV2500000
MDL号：MFCD00075290
外观与性状：淡黄色-米色粉末
密度：1.37g/cm3
沸点：597.9ºC at 760 mmHg
熔点：183-184°C(lit.)
闪点：210.2ºC
稳定性：Stable under normal temperatures and pressures.
储存条件：2-8ºC
安全说明：S36/37/39-S45
危险类别码：R23/25
WGK Germany：3
海关编码：2942000000
危险品运输编码：UN 3462 6.1/PG 2
危险类别：6.1(a)
包装等级：II
危险品标志：T
信号词：Danger
危险性防范说明：P261; P280; P302 + P350; P305 + P351 + P338; P310
危险标志：GHS06
危险性描述：H301; H310; H315; H319; H335
简介：Podophyllotoxin(abbreviatedasPPT),otherwiseknownaspodofilox,isanon-alkaloidtoxinlignanextractedfromtherootsandrhizomesofPodophyllumspecies.UnderthetradenamesCondylox,agel,andWartec,asolutionorcream,itisusedontheskinasatopicaltreatmentofexternalgenitalwarts,causedbysometypesofthehumanpapillomavirus(HPV),andotherwarts.PPTanditssyntheticderivativesdisplayawideselectioninmedicalapplicationssuchaspurgative,vesicant,antirheumatic,antiviral,andantitumoragents.Thesederivativesincludeetoposideandteniposide.Theiranticanceractivityhasbeenheavilyunderstudyandusedinvariouschemotherapies,includinglungcancer,lymphomas,andgenitaltumors.
用途：主要用于尖锐湿疣,也可用于其他病毒疣。
抗生素
