CAS号:86933-75-7
品名:神经激肽BNeurokininB(human,porcine)
中文别名:β-Neurokinin;
英文别名:NEUROMEDINK;NEUROKININB;NEUROKININK;NeurokininBNKB;NKB;DMHDFFVGLM-NH2;
分子式:C55H79N13O14S2
分子量:1210.42
精确质量:1209.53
Psa:484.89
MDL号:MFCD00133665
PubChem号:24897694
密度:1.313 g/cm3
沸点:1646ºC at 760 mmHg
闪点:949.3ºC
折射率:1.591
储存条件:-20ºC
简介:NeurokininB(NKB)belongsinthefamilyoftachykininpeptides.NeurokininBisimplicatedinavarietyofhumanfunctionsandpathwayssuchasthesecretionofgonadotropin-releasinghormone.Additionally,NKBisassociatedwithpregnancyinfemalesandmaturationinyoungadults.ReproductivefunctionishighlydependentonlevelsofbothneurokininBandalsotheG-proteincoupledreceptorligandkisspeptin.ThefirstNKBstudiesdoneattemptedtoresolvewhyhighlevelsofthepeptidemaybeimplicatedinpre-eclampsiaduringpregnancy.NKB,kisspeptin,anddynorphintogetherarefoundinthearcuatenucleus(ARC)knownastheKNDysubpopulation.ThissubpopulationistargetedbyalargenumberofsteroidhormonesandworkstoformanetworkthatfeedsbacktoGnRHpulsegenerator.
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