CAS:698387-09-6
698387-09-6
CAS号：698387-09-6
品名：来那替尼Neratinib
中文别名：(2E)-N-[4-[[3-氯-4-[(吡啶-2-基)甲氧基]苯基]氨基]-3-氰基-7-乙氧基喹啉-6-基]-4-(二甲基氨基)丁-2-烯酰胺;
英文别名：(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide;(E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide;(2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide;[2H]-Neratinib;(E)-N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide;Neratinib(HKI-272);S2150_Selleck;HKI272;(E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamidefreebase;
分子式：C30H29ClN6O3
分子量：557.043
精确质量：556.199
Psa：112.4
MDL号：MFCD09752958
密度：1.337 g/cm3
沸点：756.97ºC at 760 mmHg
闪点：411.601ºC
简介：Anoral,irreversibledualEGFR/HER2inhibitorforbreastandnon-smallcelllungcancer.Antitumoragent.
蛋白酪氨酸激酶
