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CAS:453562-69-1
453562-69-1
CAS号：453562-69-1
品名：莫特塞尼motesanib
中文别名：莫替沙尼;N-(2,3-二氢-3,3-二甲基-1H-吲哚-6-基)-2-[(4-吡啶甲基)氨基]-3-吡啶甲酰胺;3-吡啶甲酰胺,N-(2,3-二氢-3,3-二甲基-1H-吲哚-6-基)-2-[(4-吡啶基甲基)氨基];
英文别名：MotesanibBase;
分子式：C22H23N5O
分子量：373.451
精确质量：373.19
Psa：78.94
MDL号：MFCD10567689
密度：1.251
沸点：517.258ºC at 760 mmHg
折射率：1.669
简介：Motesanib(AMG706)isanexperimentaldrugcandidateoriginallydevelopedbyAmgenbutisnowbeinginvestigatedbytheTakedaPharmaceuticalCompany.ItisanorallyadministeredsmallmoleculebelongingtoangiokinaseinhibitorclasswhichactsasanantagonistofVEGFreceptors,platelet-derivedgrowthfactorreceptors,andstemcellfactorreceptors.Itisusedasthephosphatesaltmotesanibdiphosphate.
蛋白酪氨酸激酶
