CAS:849217-68-1
849217-68-1
CAS号：849217-68-1
品名：N-(4-(6,7-二甲氧基喹啉-4-基氧基)苯基)-N-(4-氟苯基)环丙烷-1,1-二羧酰胺cabozantinib
中文别名：博卡替尼;卡博替尼;N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]苯基]-N'-(4-氟苯基)-1,1-环丙烷二甲酰胺;卡赞替尼;
英文别名：N-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;cyclopropane-1,1-dicarboxylicacid[4-(6,7-dimethoxy-quinoline-4-yloxy)-phenyl]-amide(4-fluoro-phenyl)-amide;[14C]-Cabozantinib;UNII-1C39JW444G;1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;Cometriq;XL184;Cabozantinib;
分子式：C28H24FN3O5
分子量：501.506
精确质量：501.17
Psa：98.78
UNII号：1C39JW444G
密度：1.397 g/cm3
沸点：758.075ºC at 760 mmHg
闪点：412.269ºC
海关编码：2933499090
简介：Cabozantinib,marketedunderthetradenameCabometyxamongothers,isasmallmoleculeinhibitorofthetyrosinekinasesc-MetandVEGFR2,andhasbeenshowntoreducetumorgrowth,metastasis,andangiogenesis.ItwasdiscoveredanddevelopedbyExelixisInc.
蛋白酪氨酸激酶
