CAS:287383-59-9
287383-59-9
CAS号：287383-59-9
品名：Scriptaid6-(1,3-dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide
中文别名：Scriptaid
英文别名：GNF-PF-2024;CGK1026;Scriptide,GCK1026;1H-Benz[de]isoquinoline-2(3H)-hexanamide,N-hydroxy-1,3-dioxo;Scriptide;scriptaid;
分子式：C18H18N2O4
分子量：326.347
精确质量：326.127
Psa：88.4
密度：1.338g/cm3
折射率：1.646
储存条件：-20ºC
海关编码：2933990090
简介：Scriptaidisadrugwhichactsasahistonedeacetylaseinhibitor,andwasoneofthefirstcompoundsdiscoveredviahigh-throughputscreeningthatactsatthistarget.Scriptaiditselfwasneverdevelopedformedicalapplications,butledtothedevelopmentofstructurallyrelateddrugssuchasvorinostatwhichhavebeenacceptedintoclinicaluse.Mostearlyresearchusingthesecompoundsfocusedontheiranti-canceractivity,butmorerecentresearchhasfoundscriptaidtobeusefulinotherapplicationssuchascloningandresearchintoregulationofmetabolism.
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