CAS:1062161-90-3
1062161-90-3
CAS号：1062161-90-3
品名：WYE-687;N-[4-[4-(4-吗啉基)-1-[1-(3-吡啶甲基)-4-哌啶基]-1H-吡唑并[3,4-d]嘧啶-6-基]苯基]氨基甲酸甲酯methylN-[4-[4-morpholin-4-yl-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]carbamate
中文别名：WYE-687;N-[4-[4-(4-吗啉基)-1-[1-(3-吡啶甲基)-4-哌啶基]-1H-吡唑并[3,4-d]嘧啶-6-基]苯基]氨基甲酸甲酯
英文别名：pyrazolopyrimidine,9;WYE-687;,WYE687,WYE687;
分子式：C28H32N8O3
分子量：528.605
精确质量：528.26
Psa：110.53
密度：1.4±0.1g/cm3
沸点：633.2±55.0°Cat760mmHg
闪点：336.7±31.5°C
折射率：1.708
储存条件：-20℃
蒸汽压：0.0±1.9mmHgat25°C
简介：WYE-687isanATP-competitiveandselectiveinhibitorofmammaliantargetofrapamycin(mTOR).StudieshaveshownthecombinationofRas-Raf-MEK1/2inhibitorswithWYE-687mayovercomeresistancetomTorKIsthusmaybeaneffectiveadditivetherapyfortreatmentofpatientwithrenalcellcarcinomaorcolorectalcancer.
PI3K/Akt/mTOR
