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CAS:1032350-13-2
1032350-13-2
CAS号：1032350-13-2
品名：8-[4-(1-氨基环丁基)苯基]-9-苯基-1,2,4-三唑并[3,4-f][1,6]萘啶-3(2H)-酮二盐酸盐MK-2206
中文别名：8-[4-(1-氨基环丁基)苯基]-9-苯基-1,2,4-噻唑并[3,4-f][1,6]萘啶-3(2H)-酮双盐酸盐;
英文别名：MK-2206
分子式：C25H23Cl2N5O
分子量：480.389
精确质量：479.128
Psa：89.07
UNII号：Q34I3E28IO
密度：
简介：AZD6244andMK2206aretargetedsmall-moleculedrugsthatinhibitMEKandAKTresponses.ThecombinationofAZD6244andMK2206hasasignificantsynergisticeffectontumorgrowthinvitroandinvivoandleadstoincreasedsurvivalratesinmicebearinghighlyaggressivehumanlungtumors.Antitumoragents.
PI3K/Akt/mTOR
