CAS:1207360-89-1
1207360-89-1
CAS号：1207360-89-1
品名：GDC-0349;N-Ethyl-N'-[4-[5,6,7,8-四氢-4-[(3S)-3-甲基-4-吗啉基]-7-(3-氧杂环丁基)吡啶并[3,4-d]嘧啶-2-基]苯基]脲1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
中文别名：GDC-0349;N-Ethyl-N'-[4-[5,6,7,8-四氢-4-[(3S)-3-甲基-4-吗啉基]-7-(3-氧杂环丁基)吡啶并[3,4-d]嘧啶-2-基]苯基]脲
英文别名：GDC-0349||GDC0349;(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea;GDC-0349;
分子式：C24H32N6O3
分子量：452.549
精确质量：452.254
Psa：95.34
MDL号：MFCD22417087
密度：1.3±0.1g/cm3
沸点：571.3±50.0°Cat760mmHg
闪点：299.3±30.1°C
折射率：1.620
储存条件：-20℃
蒸汽压：0.0±1.6mmHgat25°C
简介：N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]ureaisapotentandselectivemTORinhibitorwithdose-dependentefficacyinmousexenograftcancermodels.
PI3K/Akt/mTOR
