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CAS:1001264-89-6
1001264-89-6
CAS号：1001264-89-6
品名：Ipatasertib
中文别名：Ipatasertib
英文别名：RG7440;GDC-0068;(2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one;
分子式：C24H32ClN5O2
分子量：457.996
精确质量：457.224
Psa：81.59
MDL号：MFCD22124514
密度：1.3±0.1g/cm3
沸点：669.4±55.0°Cat760mmHg
闪点：358.7±31.5°C
折射率：1.603
储存条件：-20℃
蒸汽压：0.0±2.1mmHgat25°C
简介：(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanoneisahighlyselectiveAKTinhibitortargetingAkt1,Akt2andAkt3.Studieshaveshownitsuseincombinationwithvemurafenib,havedemonstratedtherapeuticvalueinthetreatmentofhyperproliferativedisorderssuchascancer.
PI3K/Akt/mTOR
