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CAS:957054-30-7
957054-30-7
CAS号：957054-30-7
品名：4-羟基-2,6-二甲基苯甲腈pictrelisib
中文别名：2-(1H-吲唑-4-基)-6-[[4-(甲基磺酰基)-1-哌嗪基]甲基]-4-(4-吗啉基)噻吩并[3,2-d]嘧啶;
英文别名：GDC-0941;4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine;GDC-0941bismesylate;Pictilisib;
分子式：C23H27N7O3S2
分子量：513.636
精确质量：513.162
Psa：144.17
密度：1.53 g/cm3
折射率：1.753
简介：GDC-0941isapotentandselectiveoralinhibitoroftheclassIPI3K.GDC-0941demonstratedbroadspectrumofactivityinbreast,ovarian,lung,andprostatecancermodels.StudieshasalsoshownGDC-0941mayenhanceanti-tumoractivityofDocetaxelinhumanbreastcancermodels.
PI3K/Akt/mTOR
