CAS:873857-62-6
873857-62-6
CAS号：873857-62-6
品名：非达霉素fidaxomicin
中文别名：非达霉素
英文别名：ClostomicinB1;Fidaxomicin;
分子式：C52H74Cl2O18
分子量：1058.04
精确质量：1056.43
Psa：266.66
UNII号：Z5N076G8YQ
密度：
简介：Fidaxomicin(tradenamesDificid,Dificlir,andpreviouslyOPT-80andPAR-101)isthefirstinanewclassofnarrowspectrummacrocyclicantibioticdrugs.ItisafermentationproductobtainedfromtheactinomyceteDactylosporangiumaurantiacumsubspecieshamdenesis.Fidaxomicinisnon-systemic,meaningitisminimallyabsorbedintothebloodstream,itisbactericidal,andithasdemonstratedselectiveeradicationofpathogenicClostridiumdifficilewithminimaldisruptiontothemultiplespeciesofbacteriathatmakeupthenormal,healthyintestinalflora.ThemaintenanceofnormalphysiologicalconditionsinthecoloncanreducetheprobabilityofClostridiumdifficileinfectionrecurrence.;ItismarketedbyCubistPharmaceuticalsafteracquisitionofitsoriginatingcompanyOptimerPharmaceuticals.ThetargetuseisfortreatmentofClostridiumdifficileinfection.
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