CAS:2016-88-8
2016-88-8
CAS号：2016-88-8
品名：盐酸阿米洛利amiloridehydrochloride
中文别名：阿米洛利;阿米洛利盐酸盐水合物;N-脒基-3,5-二氨基-6-氯吡嗪甲酰胺盐酸盐;氨氯吡咪;
英文别名：AMIPRAMIDIN;amiloridechloride;AMipraMidine;N-Amidino-3,5-diamino-6-chloropyrazinecarboxamidehydrochloridehydrate;GUANAMPRAZINE;Arumil;Amiloridhydrochlorid;HCLAMILORIDEHCL;Amiloride(hydrochloride);3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamideHydrochlorideHydrate;AMipraMizi;amiprazidine;AMIPRAMIZIDE;AmilorideHCl;Amiloridehydrochloride;N-amidino-3,5-diamino-6-chloropyrazinecarboxamidehydrochloride;AMILORIDEHCL;3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamidehydrochloride;
分子式：C6H9Cl2N7O
分子量：266.088
精确质量：265.025
Psa：156.79
RTECS号：UQ2275500
EINECS号：217-958-2
MDL号：MFCD00058197
PubChem号：24277817
外观与性状：淡黄色固体
密度：2.11 g/cm3
沸点：628.1ºC at 760 mmHg
熔点：293-294°C
闪点：333.7ºC
储存条件：Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
蒸汽压：1.08E-15mmHg at 25°C
安全说明：S36-S45
危险类别码：R25
WGK Germany：3
海关编码：29339980
危险品运输编码：UN 2811 6.1/PG 3
危险类别：6.1(a)
包装等级：II
危险品标志：T
简介：Amilorideisapotassium-sparingdiuretic,firstapprovedforusein1967(thenknownasMK870),usedinthemanagementofhypertensionandcongestiveheartfailure.Amiloridewasalsotestedastreatmentofcysticfibrosis,butitwasrevealedinefficientinvivoduetoitsshorttimeofaction,thereforelonger-actingepithelialsodiumchannel(ENaC)inhibitorsmayprovemoreeffective,e.g.benzamil.
用途：为较强的保钾利尿药，常和氢氯噻嗪、呋塞米合用，因不经肝代谢，肝功能损害者仍可应用。
其他分子
