CAS号:173334-57-1
品名:阿利吉仑Aliskiren
中文别名:(2S,4S,5S,7S)-5-氨基-N-(2-氨基甲酰基-2-甲基丙基)-4-羟基-2-异丙基-7-[4-甲氧基-3-(3-甲氧基丙氧基)苄基]-8-甲基壬酰胺;阿利克仑;
英文别名:SPP100;(2S,4S,5S,7S)-5-Amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanamide;Rasilez;Tekturna;(aS,S,dS,zS)-d-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)--hydroxy-4-methoxy-3-(3-methoxypropoxy)-a,z-bis(1-methylethyl)benzeneoctanamide;(2S,4S,5S,7S)-7-(3-(3-Methoxypropoxy)-4-methoxybenzyl)-5-amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-2-isopropyl-8-methylnonanamidehydrochloride;
分子式:C30H53N3O6
分子量:551.758
精确质量:551.393
Psa:146.13
UNII号:502FWN4Q32
密度:1.067 g/cm3
沸点:748.4ºC at 760 mmHg
闪点:406.4ºC
蒸汽压:1.12E-24mmHg at 25°C
简介:Aliskiren(tradenamesTekturnaandRasilez)isthefirstinaclassofdrugscalleddirectrenininhibitors.Itsisusedforessential(primary)hypertension.Whileusedforhighbloodpressure,otherbetterstudiedmedicationsaretypicallyrecommendedduetoconcernsofhighersideeffectsandlessevidenceofbenefit.
用途:抗高血压药物、肾素抑制剂。
其他分子