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CAS:552-94-3

 552-94-3

552-94-3

CAS号:552-94-3

品名:双水杨酸酯salsalate

中文别名:水杨酸-2-羧基苯酯;水杨酸2-羧基苯酯;甲磺酸依普罗沙坦;水杨基水杨酸;2-羟基苯甲酸-2-羧基苯基酯;阿司匹林杂质E;

英文别名:Benzoicacid,2-hydroxy-,2-carboxyphenylester;2-salicyloyloxy-benzoicacid;2-(2-hydroxybenzoyl)oxybenzoicacid;Salicylsalicylicacid;Saloxium;Disalcid;Diacesal;Disalicylicacid;Sasapyrine;Diplosal;Salicylsalicylate;carboxyphenylsalicylate;Disalyl;Salsalate;sasapyrine;Sasapyrinum;

分子式:C14H10O5

分子量:258.226

精确质量:258.053

Psa:83.83

RTECS号:DH2080000

UNII号:V9MO595C9I

外观与性状:晶体

密度:1.404g/cm3

沸点:482.9ºC at 760 mmHg

熔点:139-151 °C

闪点:188ºC

稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.

储存条件:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

安全说明:37/39-26

危险类别码:R36/37/38

海关编码:2918230000

危险品标志:Xi

简介:Salsalateisamedicationthatbelongstothesalicylateandnon-steroidalanti-inflammatorydrug(NSAID)classes.RelativetootherNSAIDs,salsalatehasaweakinhibitoryeffectonthecyclooxygenaseenzymeanddecreasestheproductionofseveralproinflammatorychemicalsignalssuchasinterleukin-6,TNF-alpha,andC-reactiveprotein.ThemechanismthroughwhichsalsalateisthoughttoreducetheproductionoftheseinflammatorychemicalsignalsisthroughtheinhibitionofIκBkinaseresultingindecreasedactionofNF-κBgenes.Thismechanismisthoughttoberesponsibleforsalsalate'sinsulin-sensitizingandbloodsugarloweringproperties.SalsalateisthegenericnameofaprescriptiondrugmarketedunderthebrandnamesMono-Gesic,Salflex,Disalcid,andSalsitab.Othergenericandbrandnameformulationsmaybeavailable.

用途:非甾体抗炎药。

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