CAS号:552-94-3
品名:双水杨酸酯salsalate
中文别名:水杨酸-2-羧基苯酯;水杨酸2-羧基苯酯;甲磺酸依普罗沙坦;水杨基水杨酸;2-羟基苯甲酸-2-羧基苯基酯;阿司匹林杂质E;
英文别名:Benzoicacid,2-hydroxy-,2-carboxyphenylester;2-salicyloyloxy-benzoicacid;2-(2-hydroxybenzoyl)oxybenzoicacid;Salicylsalicylicacid;Saloxium;Disalcid;Diacesal;Disalicylicacid;Sasapyrine;Diplosal;Salicylsalicylate;carboxyphenylsalicylate;Disalyl;Salsalate;sasapyrine;Sasapyrinum;
分子式:C14H10O5
分子量:258.226
精确质量:258.053
Psa:83.83
RTECS号:DH2080000
UNII号:V9MO595C9I
外观与性状:晶体
密度:1.404g/cm3
沸点:482.9ºC at 760 mmHg
熔点:139-151 °C
闪点:188ºC
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
安全说明:37/39-26
危险类别码:R36/37/38
海关编码:2918230000
危险品标志:Xi
简介:Salsalateisamedicationthatbelongstothesalicylateandnon-steroidalanti-inflammatorydrug(NSAID)classes.RelativetootherNSAIDs,salsalatehasaweakinhibitoryeffectonthecyclooxygenaseenzymeanddecreasestheproductionofseveralproinflammatorychemicalsignalssuchasinterleukin-6,TNF-alpha,andC-reactiveprotein.ThemechanismthroughwhichsalsalateisthoughttoreducetheproductionoftheseinflammatorychemicalsignalsisthroughtheinhibitionofIκBkinaseresultingindecreasedactionofNF-κBgenes.Thismechanismisthoughttoberesponsibleforsalsalate'sinsulin-sensitizingandbloodsugarloweringproperties.SalsalateisthegenericnameofaprescriptiondrugmarketedunderthebrandnamesMono-Gesic,Salflex,Disalcid,andSalsitab.Othergenericandbrandnameformulationsmaybeavailable.
用途:非甾体抗炎药。
其他分子