CAS:193275-84-2

193275-84-2

CAS号：193275-84-2

品名：洛那法尼LONAFARNIB

中文别名：克利贝特.环已双妥明;克利贝特;4-[2-[4-[(11R)-3,10-二溴-8-氯-6,11-二氢-5H-苯并[5,6]环庚并[1,2-b]吡啶-11-基]-1-哌啶基]-2-氧代乙基]-1-哌啶甲酰胺;

英文别名：1-PiperidinecarboxaMide,4-[2-[4-[(11R)-3,10-dibroMo-8-chloro-6;4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylicacidamide;4-{2-[4-(3,10-dibromo-8-chloro-6,ll-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylicacidamide;4-[2-[4-[(11R)-3,10-DibroMo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1;[14C]-Lonafarnib;LonafarMib;Sarasar;Lonafarnib[usan];(+)-4-[2-[4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo-[5,6]cyclohepta[1,2-b]-pyridin-11(R)-yl)-1-piperidinyl]-2-oxo-ethyt]-1-piperidinecarboxamide;

分子式：C27H31Br2ClN4O2

分子量：638.822

精确质量：636.05

Psa：79.53

密度：1.536

沸点：710.4ºC at 760mmHg

闪点：383.5ºC

信号词：Warning

危险性防范说明：P305 + P351 + P338

危险标志：GHS07

危险性描述：H315; H319; H335

简介：Lonafarnibisafarnesyltransferaseinhibitor(FTI)thatisbeinginvestigatedinahumanclinicaltrialasapotentialtreatmentforprogeria.