CAS:848141-11-7
848141-11-7
CAS号：848141-11-7
品名：Alvelestat
中文别名：Alvelestat
英文别名：N-((5-(methanesulfonyl)pyridin-2-yl)methyl)-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide;AZD9668;6-methyl-1-(3-trifluoromethylphenyl)-5-(2-methylpyrazol-3-yl)-N-[(5-methylsulfonylpyridin-2-yl)methyl]-2-oxopyridine-3-carboxamide;3-Pyridinecarboxamide,1,2-dihydro-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-N-[[5-(methylsulfonyl)-2-pyridinyl]methyl]-2-oxo-1-[3-(trifluoromethyl)phenyl]-;
分子式：C25H22F3N5O4S
分子量：545.533
精确质量：545.134
Psa：124.33
外观与性状：米色至黄色固体
密度：
简介：Avelstatinhibitsplasmaneutrophilelastase(NE)activityinzymosan-stimulatedwholeblood,andalsoinhibitsNEactivityonthesurfaceofstimulatedpolymorphonuclearcellsandinthesupernatantofprimed,stimulatedcells.
代谢
