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CAS:238750-77-1

 238750-77-1

238750-77-1

CAS号:238750-77-1

品名:托舍多特Tosedostat

中文别名:ALPHA-[[(2R)-2-[(1S)-1-羟基-2-(羟基氨基)-2-氧代乙基]-4-甲基-1-氧代戊基]氨基]苯乙酸环戊酯;他达拉非;

英文别名:cyclopentyl(2S)-2-[[(2R)-2-[(1S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl]amino]-2-phenylacetate;CHR2797-Tosedostat;CHR-2797;UNII-KZK563J2UW;

分子式:C21H30N2O6

分子量:406.473

精确质量:406.21

Psa:124.96

密度:1.24

折射率:1.566

简介:CHR-2797isanovelmetalloenzymeinhibitorthatisconvertedintoapharmacologicalactiveacidproduct(CHR-79888)insidecells.CHR-2797exertsantiproliferativeeffectsagainstarangeoftumorcelllinesinvitroandinvivoandshowsselectivityfortransformedovernontransformedcells.Itsantiproliferativeeffectsareatleast300timesmorepotentthantheprototypicalaminopeptidaseinhibitor,Bestatin.

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