CAS:202825-46-5
202825-46-5
CAS号：202825-46-5
品名：沙芬酰胺甲磺酸盐Safinamidemesylatesalt
中文别名：马波沙星,麻保沙星;
英文别名：SafinamideMesylate;(2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide,methanesulfonicacid;(S)-2-(4-(3-fluorobenzyloxy)benzylamino)propanamide,methanesulfonate;(S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide;PNU-151774E,NW-1015;FCE-28073(R-isomer),PNU-151774E,NW-1015;(S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide;
分子式：C18H23FN2O5S
分子量：398.449
精确质量：398.131
Psa：127.1
MDL号：MFCD15145475
密度：
沸点：476.7ºC at 760 mmHg
闪点：242.1ºC
蒸汽压：2.98E-09mmHg at 25°C
海关编码：2924299090
信号词：Danger
危险性防范说明：P273; P280; P301 + P310; P305 + P351 + P338
危险标志：GHS05, GHS06, GHS09
危险性描述：H301; H318; H400
简介：Safinamide(INN;brandnameXadago,formerdevelopmentalcodenameEMD-1195686)isadrugindicatedforthetreatmentofParkinson'sdiseasewithmultiplemethodsofaction.In2007,aPhaseIIIclinicaltrialwasstarted.Itwasscheduledtorununtil2011.ThecompoundwasoriginallydiscoveredatFarmitalia-CarloErba,firstpublishedin1998anddevelopedbyNewronPharmaceuticals,whichsoldtherightstoMerck-Seronoin2006.InOctober2011Merck-SeronoannouncedthattheywouldgiveallrightstodevelopthecompoundbacktoNewron.
代谢
