CAS号:96314-96-4
品名:钙荧光指示剂-1Indo-1dye
中文别名:INDO1;
英文别名:INDO-1,PentapotassiumSalt;2-[4-[bis(carboxymethyl)amino]-3-[2-[2-[bis(carboxymethyl)amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylicacid;Indo1;
分子式:C32H31N3O12
分子量:649.601
精确质量:649.191
Psa:227.23
密度:1.527g/cm3
沸点:1016.3ºC at 760mmHg
折射率:1.707
储存条件:-20ºC
安全说明:S22-S24/25
简介:Indo-1isapopularcalciumindicatorsimilartoFura-2.IncontrasttoFura-2,Indo-1hasadualemissionspeak.Themainemissionpeakincalcium-freesolutionis475nmwhileinthepresenceofcalciumtheemissionisshiftedto400nm.Itiswidelyusedinflowcytometry.Thepentapotassiumsaltiscommerciallyavailableandpreferredtothefreeacidbecauseofitshighersolubilityinwater.WhileIndo-1isnotcellpermeablethepentaacetoxymethylesterIndo-1AMentersthecellwhereitiscleavedbyintracellularesterasestoIndo-1.ThesynthesisandpropertiesofIndo-1werepresentedin1985bythegroupofRogerYTsien.
荧光探针,标记,颗粒和染色