CAS:571170-77-9
571170-77-9
CAS号：571170-77-9
品名：拉罗皮兰Laropiprant
中文别名：(R)-2-(4-(4-氯苄基)-7-氟-5-(甲基磺酰基)-1,2,3,4-四氢环戊烷并[B]吲哚-3-基)乙酸;(3R)-4-[(4-氯苯基)甲基]-7-氟-1,2,3,4-四氢-5-(甲基磺酰基)-环戊并[b]吲哚-3-乙酸;
英文别名：(3R)-[4-(4-chlorobenzyl)-7-fluoro-5-(methane-sulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]aceticacid;laropiprant;MK0524;Laropiprant(INN/USAN);[(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]aceticacid;(-)-[4-(4-chlorobenzyl)-7-fluoro-5-(methanesulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]-indol-3-yl]aceticacid;UNII-G7N11T8O78;[(3R)-4-(4-chlorophenyl)methyl-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]aceticacid;Cyclopent[b]indole-3-aceticacid,4-[(4-chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)-,(3R)-;2-[(3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-5-methylsulfonyl-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]aceticacid;
分子式：C21H19ClFNO4S
分子量：435.896
精确质量：435.071
Psa：84.75
UNII号：G7N11T8O78
外观与性状：白色至米黄色固体
密度：1.486 g/cm3
沸点：710.014ºC at 760 mmHg
熔点：175∶ºC
闪点：383.203ºC
简介：Laropiprant(INN)wasadrugusedincombinationwithniacintoreducebloodcholesterol(LDLandVLDL)thatisnolongersold,duetoincreasesinside-effectswithnocardiovascularbenefit.Laropiprantitselfhasnocholesterolloweringeffect,butitreducesfacialflushesinducedbyniacin.
G蛋白偶联受体&G蛋白
