CAS:65576-45-6
65576-45-6
CAS号：65576-45-6
品名：阿塞那平Asenapine
中文别名：反式-5-氯-2,3,3A,12B-四氢-2-甲基-1H-二苯并[2,3:6,7]氧杂卓并[4,5-C]吡咯;马来酸阿莫沙平;
英文别名：trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz&<2,3:6,7&>oxepino&<4,5-c&>pyrrolidine;scorbicpalmitate;VitaminCPalmitate;L-AscorbicAcid6-Palmitate;6-palmitoylascorbicacid;&<36Cl&>-trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz&<2,3:6,7&>oxepino&<4,5-c&>pyrrole;
分子式：C17H16ClNO
分子量：285.768
精确质量：285.092
Psa：12.47
EINECS号：265-829-4
密度：1.231
沸点：357.9ºC at 760 mmHg
闪点：170.2ºC
折射率：1.609
海关编码：2934999090
简介：Asenapine(USAN,rINNMandBANM;tradenamesSaphris(AU,US,RU),Sycrest(EU,UK))isanatypicalantipsychoticdevelopedforthetreatmentofschizophreniaandacutemaniaassociatedwithbipolardisorderbySchering-PloughafteritsNovember19,2007mergerwithOrganonInternational.Developmentofthedrug,throughPhaseIIItrials,beganwhileOrganonwasstillapartofAkzoNobel.Preliminarydataindicatethatithasminimalanticholinergicandcardiovascularsideeffects,aswellasminimalweightgain.Over3000patientshaveparticipatedinclinicaltrialsofasenapine,andtheFDAapprovedthemanufacturer'sNDAinAugust2009.
G蛋白偶联受体&G蛋白
