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CAS:129497-78-5

 129497-78-5

129497-78-5

CAS号:129497-78-5

品名:维替泊芬Verteporfin

中文别名:微替泊芬;

英文别名:Verteprofin;Verteporphin;trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionicacid3,4,9-trimethylester;Visudyne;VERTEPORFIN(200MG);

分子式:C82H84N8O16

分子量:1437.59

精确质量:1436.6

Psa:337.48

UNII号:0X9PA28K43

外观与性状:暗绿色至黑色固体

密度:

简介:Verteporfin(tradenameVisudyne),abenzoporphyrinderivative,isamedicationusedasaphotosensitizerforphotodynamictherapytoeliminatetheabnormalbloodvesselsintheeyeassociatedwithconditionssuchasthewetformofmaculardegeneration.Verteporfinaccumulatesintheseabnormalbloodvesselsand,whenstimulatedbynonthermalredlightwithawavelengthof689nminthepresenceofoxygen,produceshighlyreactiveshort-livedsingletoxygenandotherreactiveoxygenradicals,resultinginlocaldamagetotheendotheliumandblockageofthevessels.

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