细胞凋亡

CAS号：1005342-46-0

品名：LCL161

中文别名：LCL161

英文别名：N1-(1H-benzimidazol-2-ylmethyl)-N1-(5,6,7,8-tetrahydro-quinolin-8-yl)-butane-1,4-diamine;(S)-(N'-(1H-benzimidazol-2-ylmethyl)-N'-(5,6,7,8-tetrahydroquinolin-8-yl))-1,4-butanediamine;(S)-N'-((1H-benzo[d]imidazol-2-yl)methyl)-N'-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine;(S)-N-((S)-1-cyclohexyl-2-{(S)-2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide;(S)-N'-(1H-benzimidazol-2-ylmethyl)-N'-(5,6,7,8-tetrahydro-quinolin-8-yl)-butane-1,4-diamine;N'-(1H-benzimidazol-2-ylmethyl)-N'-(S)-5,6,7,8-tetrahydro-quinolin-8-yl-butane-1,4-diamine;(S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine;AMD070;Propanamide,N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-,(2S)-;N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N²-methylalaninamide;

分子式：C26H33FN4O3S

分子量：500.629

精确质量：500.226

Psa：123.13

MDL号：MFCD23160049

外观与性状：米色至黄色固体

密度：

蛋白酪氨酸激酶

CAS号：332012-40-5

品名：替拉替尼4-[[4-(4-chloroanilino)furo[2,3-d]pyridazin-7-yl]oxymethyl]-N-methylpyridine-2-carboxamide

中文别名：替拉替尼

英文别名：Telatinib,BAY57-9352,BAY57-9352;4-[({4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl}oxy)methyl]-N-methyl-2-pyridinecarboxamide;Telatinib;Bay57-9352;4-(4-chlorophenylamino)-7-(2-methylaminocarbonyl-4-pyridylmethoxy)furo-[2,3-d]pyridazine;4-(4-(4-chloro-phenylamino)-furo[2,3-d]pyridazin-7-yloxymethyl)-pyridine-2-carboxylicacidmethylamide;4-((4-(4-chlorophenylamino)furo[2,3-d]pyridazin-7-yloxy)methyl)-N-methylpicolinamide;

分子式：C20H16ClN5O3

分子量：409.826

精确质量：409.094

Psa：102.17

MDL号：MFCD18251453

密度：1.418 g/cm3

沸点：713.595ºC at 760 mmHg

闪点：385.368ºC

代谢

CAS号：1030612-90-8

品名：2H-四唑乙酸,5-[3-[4-(2-溴-5-氟苯氧基)-1-哌啶基]-5-异恶唑]-2-[5-[3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]-1,2-oxazol-5-yl]tetrazol-2-yl]aceticacid

中文别名：5-[3-[4-(2-溴-5-氟苯氧基)-1-哌啶基]-5-异恶唑基]-2H-四氮唑-2-乙酸;

英文别名：CS-0410;(5-{3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]isoxazol-5-yl}tetrazol-2-yl)aceticacid;UNII-537E7QE8LX;MK8245;(5-{3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]isoxazol-5-yl}-2H-tetrazol-2-yl)aceticacid;

分子式：C17H16BrFN6O4

分子量：467.249

精确质量：466.04

Psa：119.4

UNII号：537E7QE8LX

密度：1.8±0.1g/cm3

沸点：698.3±65.0°Cat760mmHg

闪点：376.1±34.3°C

折射率：1.737

储存条件：室温，干燥，密封

蒸汽压：0.0±2.3mmHgat25°C