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CAS:1414-45-5
1414-45-5
CAS号：1414-45-5
品名：乳酸链球菌素Nisin
中文别名：乳酸链球菌肽;乳链菌肽;
英文别名：Nisin
分子式：C143H230N42O37S7
分子量：3354.07
精确质量：3351.55
Psa：1390.67
UNII号：EN8XKG133D
密度：
简介：NisinisapolycyclicantibacterialpeptideproducedbythebacteriumLactococcuslactisthatisusedasafoodpreservative.Ithas34aminoacidresidues,includingtheuncommonaminoacidslanthionine(Lan),methyllanthionine(MeLan),didehydroalanine(Dha),anddidehydroaminobutyricacid(Dhb).Theseunusualaminoacidsareintroducedbyposttranslationalmodificationoftheprecursorpeptide.Inthesereactionsaribosomallysynthesized57-merisconvertedtothefinalpeptide.Theunsaturatedaminoacidsoriginatefromserineandthreonine,andtheenzyme-catalysedadditionofcysteineresiduestothedidehydroaminoacidsresultinthemultiple(5)thioetherbridges.
合成
