CAS:51-75-2
51-75-2
CAS号：51-75-2
品名：氮芥mechlorethamine
中文别名：双(2-氯乙基)甲胺;
英文别名：Chlormethine;Mustine;N,N-bis(2-chloroethyl)methylamine;Chlorethazine;Nitrogranulogen;N-methyl-bis-(2-chloroethyl)amine;Bis(2-chloroethyl)methylamine;Caryolysine;Embichin;Ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl-;methyl-bis-(2-chloro-ethyl)-amine;2-chloro-N-(2-chloroethyl)-N-methylethanamine;Nitrogenmustard;Mustargen;
分子式：C5H12Cl3N
分子量：192.514
精确质量：191.004
Psa：3.24
RTECS号：UC6650000
UNII号：50D9XSG0VR
外观与性状：非固定的液体
密度：1.106g/cm3
沸点：110.3ºC at 760mmHg
熔点：-60ºC
闪点：20.5ºC
折射率：1.455
储存条件：库房通风低温干燥,与食品原料分开存放
蒸汽压：18 mm Hg ( 20 °C)
安全说明：S16; S26; S36/37/39; S45
危险类别码：R11; R20/22; R24; R34
WGK Germany：3
海关编码：2921194000
危险品运输编码：2810
危险类别：6.1(a)
包装等级：II
危险品标志：F; T
简介：Chlormethine(INN,BAN),mechlorethamine(widelyusedintheUS,nottheUSAN,however)alsoknownasmustineandHN2andinformerUSSRknownasEmbichinisanitrogenmustardsoldunderthebrandnameMustargen.Itistheprototypeofalkylatingagents,agroupofanticancerchemotherapeuticdrugs.ItworksbybindingtoDNA,crosslinkingtwostrandsandpreventingcellduplication.ItbindstotheN7nitrogenontheDNAbaseguanine.Asthechemicalisablisteragent,itsuseisstronglyrestrictedwithintheChemicalWeaponsConventionwhereitisclassifiedasaSchedule1substance.
