CAS号:918504-65-1
品名:维罗非尼vemurafenib
中文别名:维罗非尼
英文别名:Vemurafenib(PLX4032,RG7204);
分子式:C23H18ClF2N3O3S
分子量:489.922
精确质量:489.073
Psa:100.3
MDL号:MFCD18074504
密度:1.474 g/cm3
海关编码:2935009090
简介:VemurafenibselectiveBRAFV600Ekinaseinhibitor;anantitumoragent.Vemurafenibfunctionsbyinhibitingtheproliferationandmitogen-activatedprotein/extracellularsignal-regulatedkinase(ERK)kinaseandERKphosphorylationinapaneloftumorcelllines,includingmelanomacelllinesexpressingBRAFV600EorothermutantBRAFproteinsalteredatcodon600.
MAPK