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CAS:627530-84-1

 627530-84-1

627530-84-1

CAS号:627530-84-1

品名:BMS5649294-[(7R,7aS)-7-hydroxy-1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile

中文别名:BMS564929

英文别名:2nw4;hydantoin,3;

分子式:C14H12ClN3O3

分子量:305.716

精确质量:305.057

Psa:84.64

UNII号:9BLW27W4X7

密度:

简介:BMS-564,929isaninvestigationalselectiveandrogenreceptormodulator,whichisbeingdevelopedbyBristol-MyersSquibbfortreatmentofthesymptomsofage-relateddeclineinandrogenlevelsinmen(\"andropause\").Thesesymptomsmayincludedepression,lossofmusclemassandstrength,reductioninlibidoandosteoporosis.Treatmentwithexogenoustestosteroneiseffectiveincounteractingthesesymptomsbutisassociatedwitharangeofsideeffects,themostseriousofwhichisenlargementoftheprostategland,whichcanleadtobenignprostatichypertrophyandevenprostatecancer.Thismeansthereisaclinicalneedforselectiveandrogenreceptormodulators,whichproduceanaboliceffectsinsometissuessuchasmuscleandbone,butwithoutstimulatingandrogenreceptorsintheprostate.

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