CAS号:627530-84-1
品名:BMS5649294-[(7R,7aS)-7-hydroxy-1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile
中文别名:BMS564929
英文别名:2nw4;hydantoin,3;
分子式:C14H12ClN3O3
分子量:305.716
精确质量:305.057
Psa:84.64
UNII号:9BLW27W4X7
密度:
简介:BMS-564,929isaninvestigationalselectiveandrogenreceptormodulator,whichisbeingdevelopedbyBristol-MyersSquibbfortreatmentofthesymptomsofage-relateddeclineinandrogenlevelsinmen(\"andropause\").Thesesymptomsmayincludedepression,lossofmusclemassandstrength,reductioninlibidoandosteoporosis.Treatmentwithexogenoustestosteroneiseffectiveincounteractingthesesymptomsbutisassociatedwitharangeofsideeffects,themostseriousofwhichisenlargementoftheprostategland,whichcanleadtobenignprostatichypertrophyandevenprostatecancer.Thismeansthereisaclinicalneedforselectiveandrogenreceptormodulators,whichproduceanaboliceffectsinsometissuessuchasmuscleandbone,butwithoutstimulatingandrogenreceptorsintheprostate.
其他分子