CAS:361444-66-8
361444-66-8
CAS号：361444-66-8
品名：JDTic;(3R)-1,2,3,4-四氢-7-羟基-N-[(1S)-1-[[(3R,4R)-4-(3-羟基苯基)-3,4-二甲基-1-哌啶基]甲基]-2-甲基丙基]-3-异喹啉甲酰胺(3R)-7-hydroxy-N-[(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
中文别名：JDTic;(3R)-1,2,3,4-四氢-7-羟基-N-[(1S)-1-[[(3R,4R)-4-(3-羟基苯基)-3,4-二甲基-1-哌啶基]甲基]-2-甲基丙基]-3-异喹啉甲酰胺
英文别名：JDC;CS-0537;JDTic;(3r)-7-Hydroxy-N-{(2s)-1-[(3r,4r)-4-(3-Hydroxyphenyl)-3,4-Dimethylpiperidin-1-Yl]-3-Methylbutan-2-Yl}-1,2,3,4-Tetrahydroisoquinoline-3-Carboxamide;
分子式：C28H39N3O3
分子量：465.628
精确质量：465.299
Psa：88.32
密度：1.1±0.1g/cm3
沸点：701.9±60.0°Cat760mmHg
闪点：378.3±32.9°C
折射率：1.570
储存条件：2-8℃
蒸汽压：0.0±2.3mmHgat25°C
简介：JDTicisaselective,long-acting(\"inactivating\")antagonistoftheκ-opioidreceptor(KOR).JDTicisa4-phenylpiperidinederivative,distantlyrelatedstructurallytoanalgesicssuchaspethidineandketobemidone,andmorecloselytotheMORantagonistalvimopan.Inaddition,itisstructurallydistinctfromotherKORantagonistssuchasnorbinaltorphimine.
G蛋白偶联受体&G蛋白
